Run dir: [v2_runs]/selfhost_qwen36_27_HER2_AAV_20260423_222338_7307349
| target | program/profile | gen | n_successful | rank_key | best_i_pae | best_plddt | description |
|---|---|---|---|---|---|---|---|
| 27_HER2_AAV | 26a44fb19f7f | 1 | 6 | 0.22149551 | 0.92071694 | Two-stage program: stage 1 uses cheap 200-step exploration with 8 samples and reduced i_pae penalty to gather diverse candidates, stage 2 clones stage 0 with higher fidelity (40... | |
| 27_HER2_AAV | 4d9ed88f945d | 1 | 0 | Switch to diverse-beam-search (width=12, diversity=1.0, parent_penalty=0.5), enable guided sampling (ag_ratio=1.0, guidance_w=1.5), and strengthen iPAE penalty to -2.0 for bette... | |||
| 27_HER2_AAV | 7a4c404b5c8c | 2 | 17 | 0.20944516 | 0.92999864 | Append a second stage with 1000-step sampling and aggressive greedy/temperature optimization to refine stage 1's diverse candidates, with step_checkpoints aligned to nsteps. | |
| 27_HER2_AAV | 7efee3dc83b2 | 1 | 0 | 0.24930906 | 0.9073316 | Switch to diverse-beam-search with higher beam_width (12) and increased diversity_weight (0.6) to promote structural diversity for better FoldSeek uniqueness. | |
| 27_HER2_AAV | 8ea63f99071d | 1 | 12 | 0.20944516 | 0.92999864 | Increase beam_width from 8 to 12 and nsamples from 4 to 8 for broader early search, reducing batch_size to 4 to maintain memory within 512 limit (12×8×4=384). | |
| 27_HER2_AAV | ae65588929b3 | 3 | Increase stage 1 nsamples to 16 and reduce beam_width to 8 to maintain memory budget, while switching stage 1 refinement to sequence hallucination for deeper polishing. | ||||
| 27_HER2_AAV | cc4c33127849 | 0 | 6 | 0.22149551 | 0.92071694 | seed (balanced baseline) | |
| 27_HER2_AAV | db68d905ebdc | 2 | 13 | 0.20944516 | 0.9348807 | Append a conditional second stage (cloned from stage 0) with doubled sampling steps (800) and intensified greedy refinement (30/10 iters) plus updated checkpoints, gated by n_su... |
Generated 2026-04-25